Research Areas

 

The mechanical genome:

nucleosome positioning rules and multiplexing

 

Nucleosome dynamics:

breathing and force-induced unwrapping

 

Genome-wide studies:

Markov chain model and uni- vs. multicellular organisms

 

Chromatin remodelers:

active Brownian dimers and kinetic proofreading

 

Chromatin at large scales:

loop extrusion and overall nuclear organization